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About ISAPP
Our mission: To engender and disseminate information on high quality, multidisciplinary, scientific investigation in the fields of probiotics and prebiotics, and to advance the development of scientifically substantiated, health-promoting probiotic and prebiotic products worldwide.
ISAPP is an association of academic and industrial scientists involved in research on fundamental and applied aspects of probiotics and prebiotics. The scientists participating in ISAPP have a common interest in generating high quality scientific information for the probiotic and prebiotic fields and providing guidance for collaborative and multidisciplinary research. The organization hopes to raise the scientific credibility of the field by working with experts and conducting meetings on high quality research. Providing an objective, science-based voice also will benefit the end users of these products by helping them make informed choices. ISAPP is the only scientific organization dedicated specifically to probiotics and prebiotics, bringing together scientists from all pertinent disciplines, including food science, microbiology, immunology, biochemistry, nutrition and medicine. As a scientific society, ISAPP strives to have all activities focused on science, not promotion of specific commercial products. Industry involvement is considered important to this organization, but no industry group or commercial entity dictates the activities or opinions of ISAPP.
ISAPP began in 2000 with the assembly of some professionals at the Fermented Foods and Health Meeting in New York. The discussion at this meeting focused on the lack of a multidisciplinary scientific organization dedicated to specifically addressing the dynamic and increasingly popular field of probiotics and prebiotics. Considering the situation world-wide of industry launching many new probiotic- and prebiotic-based functional foods, dietary supplements and clinical therapeutics, it was thought especially valuable to fill this void. ISAPP was formally established in August 2002 as a non-profit, tax-exempt 501(c)(3) corporation in California.

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Some areas of research interest are:
  • Immunology: up-regulate or down-regulate immune function; up-regulation of immune function may improve the ability to fight infections or inhibit tumor formation; down-regulation may prevent the onset of allergy or intestinal inflammation
  • Cancer: epidemiology, animal and human studies, mechanisms, role in genotoxicity
  • Gastrointestinal environmental changes induced by probiotic and prebiotic feeding: genetic-based tracking methods, microbiological, physiological and biochemical changes
  • Role in the functional food concept: comparison with other dietary approaches
  • GI tract disease: acute gastroenteritis (viruses, bacteria), lactose intolerance, diarrhea, ulcerative colitis, Crohn's disease, pseudomembranous colitis, irritable bowel syndrome
  • Emerging areas: wound healing, urogenital infections, autism, vaccine delivery, skin microbiology
  • Genetics of probiotic microbes: status of genome sequencing and future suggestions, application of the technology, role of proteomics and transcriptomics
  • Microbiological issues: taxonomy, shelf-stability, quality assurance approach, dose, delivery vehicle (food, supplement), antibiotic resistance
  • Testing efficacy: laboratory models, animal studies, human trials, clinical situation
  • Future requirements: synbiotics new product developments, distal colon activities, multi-functional approach, low dosage forms, application of robust but useable monitoring tools
Probiotics: Probiotics are defined as live microorganisms which, when administered in adequate amounts confer a health benefit on the host (FAO/WHO. 2001.)
Prebiotics: Prebiotics are non-digestible substances that provide a beneficial physiological effect on the host by selectively stimulating the favorable growth or activity of a limited number of indigenous bacteria.

Our Mission

To engender and disseminate information on high quality, multidisciplinary, scientific investigation in the fields of probiotics and prebiotics, and to advance the development of scientifically substantiated, health-promoting probiotic and prebiotic products worldwide.


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Photos courtesy of Prof. Lorenzo Morelli, Instituto di Microbiologia, Piacenza, Italy
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